Brain histamine H 1 receptor occupancy after oral administration of desloratadine and loratadine
نویسندگان
چکیده
منابع مشابه
Loratadine is an antihistaminergic drug with a tricyclic structure and a selective peripheral H-1-receptor activity [1]. Desloratadine is its primary active metabolite and is a non-sedating, long-acting histamine antagonist. After oral administration, desloratadine selectively blocks peripheral histamine H1-receptors
Loratadine is an antihistaminergic drug with a tricyclic structure and a selective peripheral H-1-receptor activity [1]. Desloratadine is its primary active metabolite and is a non-sedating, long-acting histamine antagonist. After oral administration, desloratadine selectively blocks peripheral histamine H1-receptors because the substance is excluded from entry to the central nervous system [2]...
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ژورنال
عنوان ژورنال: Pharmacology Research & Perspectives
سال: 2019
ISSN: 2052-1707,2052-1707
DOI: 10.1002/prp2.499